The RX 350 and RX 450h land squarely in the full-sized luxury SUV segment, with the amenities and horsepower to back it up. The 450h has the extra benefit of a hybrid drivetrain that can run on batteries alone for short distances. The 350 does all right on its own, doing 18 mpg city and 25 mpg highway, but the 450h really shines with 28 mpg city and 32 mpg highway.
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